In-silico Immunomodelling of SARS-CoV-2
نویسندگان
چکیده
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-strand RNA virus belonging to the Coronaviridae family, responsible for infectious disease 2019 (COVID-19) with rapid transmission. This study aimed characterize and compare SARS-CoV-2 SARS-CoV major viral proteins predict antigen proteasomal cleavage patterns, MHC class I processing presentation, B T-cell anti-inflammatory epitopes.
منابع مشابه
In silico design a multivalent epitope vaccine against SARS-CoV-2 for Iranian populations
Background: Due to high genetic variation in human leukocyte antigen )HLA( alleles, epitope-based vaccines don’t show equal efficacy in different human populations. therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity as well as conservancy level from SARS-CoV...
متن کاملSARS-CoV-2 infection: its psychiatric manifestations
Background: The clinical presentation of SARS-CoV-2 infection was initially dominated by respiratory symptoms. However the clinical spectrum is wide and neuropsychiatric syndromes are also a source of medical concern. Our aims are to present an atypical clinical presentation of SARS-CoV-2 infection characterized by auditory hallucinations and unusual behavior and to emphasize the diversity of ...
متن کاملمروری به بررسی ایمونولوژیکی SARS-Cov-2
زمینه و هدف بیماری کووید-19 یک بیماری عفونی به‌شدت مسری می‌باشد که توسط یک کروناویروس جدید ایجاد می‌شود که می‌تواند از انسان به انسان از طریق تماس نزدیک منتقل شود. هدف از مطالعه حاضر بررسی اطلاعات جدید در زمینه ایمونولوژی کووید-19 می‌باشد. مواد و روش‌ها در مطالعه مروری حاضر، از موتورهای جستجوی Google و Google Scholar و مقالات نمایه شده در پایگاه‌های علمی معتبر بین‌المللی از جمله Pub Med، MedLi...
متن کاملSARS-CoV-2: A Review Of Present & Future Perspectives
As the dawn of this new decade has begun, we have faced our arch-nemesis right at the start in the form of Coronavirus also known as COVID-19. Since its origin from Wuhan, China, it has been declared a pandemic and has effected several countries worldwide. This review article summarizes all the research, techniques, strategies, and treatment methodologies that are taking place internationally i...
متن کاملGastrointestinal Manifestations in Patients Infected with SARS-CoV-2
Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, has recently become the number one problem affecting global health. Coronavirus disease 2019 is principally recognized by its respiratory manifestations; however, recent studies have shown an increasing number of patients with gastrointestinal complaints like diarrhea, nausea, vomiting, and abdominal discomfort...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of medical microbiology and infectious diseases
سال: 2021
ISSN: ['2345-5330', '2345-5349']
DOI: https://doi.org/10.52547/jommid.9.2.88